Current Issue : October-December Volume : 2011 Issue Number : 4 Articles : 12 Articles
The development of anthelmintic resistance and the high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants as an alternative source of anthelmintics. In the current study, in-vitro experiments were conducted to determine the possible anthelmintic effects of crude ethanolic extract of Piper Betle and Moringa Oleifera against Eichenea foetida . Both the extracts were tested for two doses 25mg/ml and 50 mg/ml. Synergistic activity of both the extract was studied 1:1 extract at the dose 50 mg/ml. Results suggested that both the plants showed dose dependent effect and Piper Betle was found to be more effective than Moringa Oleifera .The overall findings of the present study have shown that Piper Betle and Moringa Oleifera contain possible anthelmintic compounds and further evaluation of these plants should be carried out....
To study anti-inflammatory activity of methanolic extract (ME) of Zanthoxylum armatum (ZA) fruit. The study was carried out using male wistar rats (180-230g). The ME was prepared using maceration process. The effect of ME of Zanthoxylum armatum (ZA) fruit was investigated for In vivo anti inflammatory activity was evaluated in wistar species of rats by using carrageenan induced rat paw edema method. The methanolic extract (ME) of Zanthoxylum armatum (ZA) fruit was used in pain and inflammation model. A Zanthoxylum armatum at doses (100mg/kg, 200mg/kg) showed significant (P< 0.05) inhibition of carrageenan induced hind paw edema in rats The methanolic extract (ME) of Zanthoxylum armatum (ZA) fruit showed significant anti-inflammatory activity in rat....
The antioxidant activity of the plant extract was measured in terms of radical scavenging ability, according to the DPPH method. The free radical scavenging activity of methanolic, aqueous and chloroform extract of Convolvulus pluricaulis plant increased with increase in concentration and was found to be 84, 83 and 48 % respectively against 93% of ascorbic acid. The present study provides evidence that the methanolic and chloroform extract of Convolvus plauricalis is a potential source of natural antioxidants....
Cynodon dactylon L. (Durva) from ancient times has a place in the heart of Hindus due to its sacred value for the lord Ganesha. In ayurveda from the era of Charka and Sushruta the herb had been of keen interest due to its wide spectrum of biological activitities. Since ancient times, plants have been an exemplary source of medicine. Cynodon dactylon L. found commonly throughout India but till yet has been reveled for its potential biological activities. The present review is an attempt made to give details of the herb along with its potential biological activities which might be a glimpse for a future research in the identification and characterization of the herb for its valuable biological activities....
Background: The aim of this study was to evaluate the antidiabetic activity of Mimusops elengi L. against dexamethasone induced diabetes in mice. As we all known, glucocorticoids can induce insulin resistance when they are administered to human or experimental animals during excess condition. Materials and Methods: Normal control group received equivalent amount of phosphate buffer saline, and 54 mice were rendered hyperglycemic by daily administration of a pre standardized dose of dexamethasone for consecutive 7 days and then divided in to nine groups of six each. Blood samples were collected and serum insulin was estimated. Biochemical estimation of Plasma glucose and serum triglyceride, serum cholesterol, Atherogenic index was done using standard diagnostic kits. Hepatic antioxidant as well as Glycogen content from liver and calf muscle was estimated after sacrificing animals on day 22. Three fractions from methanolic extract were screened. Results: Group treated with F1 (Aqueous fraction) and F2 (n-Butanol fraction) 100 mg/kg were found to be highly significant as compared with dexamethasone control group. Conclusion: Thus from the results obtained in the present investigation we can conclude that F1 and F2 may prove to be useful in treating insulin resistance as F1 and F2 is able to produce glycemic control, and increase insulin sensitivity. F1 and F2 is also endowed with in vivo antioxidant activity along with the ability to increase glycogenesis which can prove beneficial in the management of complications of insulin resistance like diabetes and diabetic complications....
Bauhinia tomentosa from the ancient time had been used for its grace values on the occasion of Dashehera by hindus.besides this Bauhinia tomentosa had been reported in literature for its wide variety of biological activities which may be proved as an a frutfull remedy for the treatment of various life threatening diseases and disorders like digestive, antibacterial, antioxidant, antifungal, stomachic and anthelmintic etc. the present review is an attempt to reveal the ethanopharmacological, phytochemical and pharmacological profiles of Bauhinia tomentosa....
The present study investigate that evaluate the wound healing activity of the plant, ethanolic extract was prepared. A study was conducted to wound healing activity of Datura metel Linn. on albino rats of Wistar strain using three different models viz, excision incision and dead space wound was studied. The granulation tissue formed on days 4, 8, 12 and 16 (post-wound) was used to estimate total collagen, hexosamine, protein, DNA and uronic acid. The extract increased cellular proliferation and collagen synthesis at the wound site, as evidenced by increase in DNA, total protein and total collagen content of granulation tissues. The extract treated wounds were found to heal much faster as indicated by improved rates of epithelialization and wound contraction, also confirmed by histopathological examinations. The extract of Datura metel Linn., significantly increased the wound breaking strength in the incision wound model compared with controls (P < 0.001). The extract-treated wounds were found to epithelialize faster, and the rate of wound contraction was significantly increased in comparison to control wounds (P < 0.001), Wet and dry granulation tissue weights in a dead space wound model increased significantly (p < 0.001). There was a significant increase in wound closure rate, tensile strength, dry granuloma weight, wet granuloma weight and decrease in epithelization period in Datura metel Linn, treated group when compared to control and commercial drug treated groups. From the results, it may be concluded that the ethanolic extract of Datura metel Linn, had greater wound healing activity than the nitrofurazone ointment...
In vitro antioxidant activity of Alcoholic & Aqeuous root extract of Tricosanthes tricuspidata was determined by DPPH free radical scavenging assay. Ascorbic acid & BHT were used as a standard. All the analysis were made with the use of U.V. visible spectrophotometer (Systronic).The alcohol & aqueous root extract of Tricosanthes tricuspidata had shown very significant DPPH (1,1 diphenyl Picryl hydrazyl) free radical scavenging activity when compared with standard antioxidants. The results shows that aqueous extract is having more antioxidant properties as compared to alcohol extract , However the results concluded that both the extract have potential source of antioxidants of natural origin....
Polypodium species of genus Polypodiaceae was investigated for preliminary phytochemical screening and microscopy. Different extracts were prepared with the help of hot extraction method by using soxhlet apparatus. Flavanoids, phytosterols, proteins, fatty acids and diterpenes were mainly detected. It was concluded that extracts of Polypodium decumanum contains important constituents which can be explored for the various pharmacological activities like antimicrobial, anthelmintic, antioxidant, anti-inflammatory etc. In microscopical examination, it was found that mainly multicellular trichomes, simple covering trichomes, fibres, epidermal cells, anomocytic stomata were present....
The aim of the present study is to evaluate the Pharmacognostical and Phytochemical studies of Aerial parts of Tabernaemontana divaricata. The plant belongs to the family Apocynaceae, a common garden plant in tropical countries has been used as antioxidant, anti-infection, anti-tumour and analgesia as a folk medicine in India, Sri Lanka, Malaysia and Thailand. Hence in the present work the Aerial parts of the plants were subjected to physical, microscopical, physiochemical and phytochemical evaluations. Microscopical transverse section of leaf showed a narrow upper epidermis with palisade, vascular bundle at the centre with a narrow zone of spongy parenchyma and a continuous mass of thin walled ground tissue towards the phariphery. T.S. of stem showed a thin elongated single layer of upper epidermis with hypodermis, followed by continuous mass of thin walled parenchymatous cells of cortex and vascular bundles containing xylem and phloem cells towards the periphery. The powdered aerial parts showed the presence of anisocytic stomata, unicellular trichomes, bundle of phloem fibres and calcium oxalate crystals. Physicochemical parameters such as ash values and extractive values and preliminary Phytochemical screening of methanolic extract of Tabernaemontana divaricata were also carried out. These findings might be useful to supplement information in regard to its identification parameters, which could help in the development of a suitable monograph for the plant....
Psorlea corylifolia and Cordia dichotoma are generally found in throughout the India, which yet to be fully explored in terms of medicinal plants. These plants posses a wide number of medicinal properties as reported in the literature and hence these are used extensively in several tribes of India to combat a number of diseases. Preliminary phamacognostic studies were carried out on the seeds of Psoralea corylifolia and fruits of Cordia dichotoma including morphological, physicochemical studies alongwith phytochemical screening. The protocol followed for elucidating physicochemical properties were as per WHO guidelines. The successive extraction of plant parts were undertaken by using various solvents of increasing polarity and the extracts thus obtained were subjected for phytochemical analysis, followed by thin layer chromatographic examination by optimizing the solvent systems. The phytochemical investigation revealed the presence of alkaloids, glycosides, flavonoids, and phenolic compounds mainly. These preliminary data may be helpful in developing the standardization parameters of plant parts....
Study of Lawsonia inermis L. (Family: Lythraceae) revealed that use of wildlife medicinal resources in a concern not only from the conservation point of view but in the therapeutic point of view. The aerial part of the plant & hairy roots of Lawsonia inermis grown in east African regions mostly. Acetone extract of Lawsonia inermis (Mehendi) leaves showed significant nootropic effect on the elevated CNS conditions. Henna, Lawsonia inermis L. (Lythraceae), is a much branched shrub that grows in middle east of Africa. This point seems to be of minor importance regarding tattooing realized with henna (Lawsonia inermis) powder or other labile vegetable substances. Cassia absus (Lawsonia alba Lam.) and yellow (Cochlospermum tinctorium) also have some similar functions of the dyeing the hair with different contents and concentrations of lawsone. The juice extracted from the leaves of the plant is and the public regarding the use of medicinal plants. The production of food, forage, medicinal products, Lawsonia inermis gives the medicinal purposes & their uses. Mehendi or henna (Lawsonia inermis) is a small tropical shrub having ayurvedic characteristic bhasma has medicinal value and is used in many ayurvedic medicines. Antibacterial activity of some medicinal plants like the ethyl acetate extract of Lawsonia inermis was found to be the most effective for their antibacterial activities....
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